Remove 2010 Remove Anaphylaxis Remove Resuscitation
article thumbnail

Vasopressor Nonresponse

Northwestern EM Blog

Due to its extremely high morbidity and mortality as well as high healthcare costs, the prompt recognition, diagnosis and resuscitation of shock is key. There is a subset of patients who, despite aggressive conventional resuscitation, have an inadequate hemodynamic response and develop refractory shock. 2010; 36: 2019-2029.

article thumbnail

Annals of B Pod: Anti-Xa Overdose

Taming the SRU

Discussion of Evidence for Management Initial management of DOAC overdose centers around establishing large-bore intravenous access and providing adequate resuscitation for hemodynamically unstable patients. This does not deviate from general resuscitation principles for acute hemorrhage. BMC Pharmacol Toxicol. May 2; 19(1): 19.

article thumbnail

Review of the ATHOS 3 trial

Northwestern EM Blog

Severe shock is defined as persistent hypotension requiring vasopressors to maintain a mean arterial pressure of 65mmHg and serum lactate <2 despite adequate volume resuscitation. Expert Review of Cardiovascular Therapy 2010; 8(12): 1723-9 PMID: 21108554 Santacruz CA, Pereira AJ, Celis E, Vincent JL. NEJM 2008; 358(9): 877 – 87.

Shock 52
article thumbnail

Grand Rounds Recap 3.15.23

Taming the SRU

massive bee envenomation - R4 Capstone - Hydrocephalus - cpc: brain tumor - hyperviscosity syndromes - the language of being well & embracing fear in emergency medicine tamingthesru: Massive bee envenomation WITH dr. Yates Anaphylaxis Pathophysiology Type 1 Hypersensitivity Reaction IgE-mediated Mast-cell degranulation of vasoactive materials Reaction (..)

article thumbnail

Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

We know that if administered too rapidly, it can lead to hypotension and other adverse effects including seizures, headaches, backache, abdominal pain, nausea, vomiting, diarrhea, fatigue, pulmonary embolism, deep vein thrombosis, anaphylaxis, impaired color vision, and other visual disturbances.[1] Lancet 2010; 376:23-32.[

article thumbnail

Episode 20 - Emergency Department Management of North American Snake Envenomations

EB Medicine

If EMS has placed bandages, leave them in place until antivenom and resuscitative equipment is ready. Jeff: Hypotension should be treated with isotonic fluids and, as usual, anaphylaxis should be treated with the usual cocktail of antihistamines and epinephrine at first IM and then via infusion if refractory. 1-800-222-1222.

article thumbnail

REBEL Core Cast 122.0 – Neutropenic Fever

RebelEM

Read More: Infectious Disease Society of America 2010 Clinical Practice Guidelines Life in the Fast Lane: Febrile Neutropaenia Uptodate: overview of neutropenic fever syndromes EMRAP: Risk stratification of neutropenic fever MDCalc: MASCC Score MDCalc: CISNE Score References: Ahn S, Rice TW, Yeung SJ, Cooksley T. Sepkowitz, K. Boeckh, M.