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Pre-Hospital Antibiotics in Sepsis?

RebelEM

Background: Sepsis remains one of the leading causes of morbidity and mortality. Prehospital Administration of Broad-Spectrum Antibiotics for Sepsis Patients: A Systematic Review and Meta-Analysis. It is well-established that earlier recognition and treatment can lead to better outcome for these patients . Health Sci Rep 2022.

Sepsis 132
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The Latest in Critical Care, 10/30/23 (Issue #18)

PulmCCM

Professional Medical Societies Call for Elimination of SEP-1 The Infectious Diseases Society of America (IDSA), along with societies for emergency medicine physicians and hospitalists, are again speaking up about the ongoing policy experiment known as the Centers for Medicare and Medicaid Severe Sepsis/Septic Shock Management Bundle (SEP-1).

Sepsis 52
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The CLOVERS Trial

Taming the SRU

Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension. doi:10.1056/NEJMoa2212663 BACKGROUND Sepsis, including severe sepsis and septic shock, is a frequently encountered condition in the emergency department and carries a high mortality rate. N Engl J Med. 2023;388(6):499-510. 2018, Kuttab, Lykins et al.

Sepsis 52
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EM@3AM: Amniotic Fluid Embolism

EMDocs

Romero (2009). “Markers of Inflammation and Infection in Sepsis and Disseminated Intravascular Coagulation.” Additionally, PE in the context of labor is less likely than AFE, given the patient’s presentation and timing. Rosh Review Website Link Further Reading: FOAM Reading: [link] References: Conde-Agudelo, A.

EMS 97
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SGEM#356: Drugs are Gonna Knock You Out – Etomidate vs. Ketamine for Emergency Endotracheal Intubation

The Skeptics' Guide to EM

A 2009 randomized control trial conducted in French ICUs supported the use of ketamine in this patient population [5]. Historically there has been concern about adrenal insufficiency caused by etomidate being harmful for patients with sepsis but this has not been shown to cause increased mortality in the literature [6, 7].

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Bubble Wrap PLUS – November ’26

Don't Forget the Bubbles

Update to the Neonatal Early-Onset Sepsis Calculator Utilizing a Contemporary Cohort. Rotavirus Vaccine Effectiveness Against Severe Acute Gastroenteritis: 2009-2022. Trends in C-Reactive Protein Use in Early-onset Sepsis Evaluations and Associated Antibiotic Use. Edwards EM, et al. Pediatrics. 2024 Oct 1;154(4):e2024065963.

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PEMPix 2023 Online Case 3: The Only Thing We Have to Fear

PEMBlog

rectally, prompting a sepsis workup given his age. Initially in the emergency department he was generally well-appearing with normal vital signs. His rash is pictured here: He subsequently developed a fever to 38.2C Labs were notable for: WBC 9.1 x 10E+09/L with ANC 4.46 Lancet (London, England), 351(9116), 1614–1619. link] Takahashi, N.,