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Diagnostics: Inflammatory Markers

Taming the SRU

A 2008 review in the International Journal of Medicine on spinal epidural abscess (SEA) agreed that inflammatory markers (specifically ESR and CRP) are generally sensitive in the diagnosis of SEA, but are not specific. 2008 Aug;75(8):557-66. Notably, up to 40% of patients with native vertebral osteomyelitis had a normal WBC [33-34].

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Antibiotics in the paediatric emergency department

Don't Forget the Bubbles

However, results may take some time and, as such, rapid point-of-care tests are increasingly used. 2008 Mar;72(3):377–83. A throat culture is the gold standard for confirming a bacterial infection. Beware of false positives from colonisation of the throat with streptococcus. Int J Pediatr Otorhinolaryngol.