Emergency Medicine Ireland

OCTOBER 30, 2023

As such vasopresin exhibits the same ADH effects but this maxes out at very low doses, much lower than what we use in sepsis. First up is the VASST trial, (Russel et al 2008 NEJM). Primary outcome here was kidney based rather than mortality. New Engl J Medicine 358 , 877–87 (2008). 400 pts here, no clear benefit for vaso.

Shock 52

Shock Sepsis Wellness Outcomes 52

The Skeptics' Guide to EM

FEBRUARY 24, 2018

The second, the larger CORTICUS study, published in the NEJM in 2008 found no benefit of the use of corticosteroids compared to placebo. This looked at hydrocortisone to prevent patients with severe sepsis in developing septic shock. Now these contradictory results could have come about for a number of reasons.

Shock 40

Shock Sepsis Emergency Department Resuscitation 40

PulmCCM

FEBRUARY 12, 2024

SCCM made its statement unilaterally, without the European Society of Intensive Care Medicine (ESICM), its partner on the 2008 and 2017 updates, or the American Thoracic Society (ATS). That could be because CIRCI is ill-defined, almost hypothetical. The new evidence prompted all three societies to issue new guideline updates.

Shock 52

Shock Administration Sepsis Fractures 52

Don't Forget the Bubbles

JUNE 10, 2024

Despite advancements in neonatal care, NEC remains a significant concern due to its association with adverse outcomes, including prolonged hospitalisation, the need for surgical intervention, and increased mortality rates. Differential diagnoses include septic ileus, and infection causes such as sepsis, meningitis and pneumonia.

Pediatrics 40

Pediatrics Sepsis Fluid Resuscitation Outcomes 40

Thinking Critical Care

MAY 18, 2023

To everybody outside Glasgow glucocorticoids seemed to be the answer and Chicago surgeon William Schumer was their chief flag waver, claiming in 1976 that steroid therapy reduced the mortality of saline-treated sepsis in his service from 33% to around 10%. [5] The Shock Team had an office with three desks, one for each of us. 311:1137-43.

Shock 40

Shock Research Sepsis Resuscitation 40

EB Medicine

JULY 8, 2019

From the 80’s to 2008, the worldwide prevalence of obesity nearly doubled! Leakage from the staple line typically presents within the first week, but can present up to 35 days, usually with fevers, tachycardia, abdominal pain, nausea, vomiting sepsis, or peritonitis. Additionally, back in 2010, it was estimated that 6.6%

Emergency Department 40

Emergency Department Sepsis Operations Dehydration 40

Don't Forget the Bubbles

AUGUST 21, 2023

Infection/sepsis? What are the long-term outcomes for children with dilated cardiomyopathy? Outcomes at 1 year seem to be influenced by the severity of illness at presentation. Outcomes at 5 years, though, are better amongst those patients admitted to intensive care. Female sex and younger age favour better outcomes.

Pediatrics 98

Pediatrics Outcomes Research Sepsis 98

RebelEM

MAY 15, 2024

Antibiotics are effectively the only thing standing between these patients and overwhelming sepsis. Improving the immediate management of neutropenic sepsis in the UK: Lessons from a national audit. 2008 Sep;1138:329-50. Time to antibiotics and outcomes in cancer patients with febrile neutropenia. Support Care Cancer.

Infectious Diseases 104

Infectious Diseases Administration Sepsis Anaphylaxis 104

EMDocs

OCTOBER 23, 2023

This may also predispose a patient to sepsis, peritonitis, or bowel infarction, which need to be recognized quickly. Morbidity outcomes of 78,577 hysterectomies for benign reasons over 23 years. BJOG 2008; 115:1473. It may present with vaginal bleeding (the most common presenting symptom) (3), or watery vaginal discharge (2,6).

OB/GYN 67

OB/GYN Operations EMS Ultrasounds 67