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SGEM#428: Don’t Worry, Be Happy – The Safety of Nitroglycerin Administration in RVMI

The Skeptics' Guide to EM

Adverse events from nitrate administration during right ventricular myocardial infarction: a systematic review and meta-analysis. Adverse events from nitrate administration during right ventricular myocardial infarction: a systematic review and meta-analysis. Fanaroff et al looked at the ACC/AHA guidelines from 2008-2018 [4].

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EM@3AM: Murine Typhus

EMDocs

6, 2008, pp. 2008 Mar 15;46(6):913-918. Food and Drug Administration. What is the diagnosis? Answer : Murine Typhus Epidemiology: Murine typhus is endemic in several parts of the U.S.: Epidemiology and Clinical Manifestations of Murine Typhus in the United States: A Review of the Literature and New Data from California.”

EMS 104
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Pre-Hospital Antibiotics in Sepsis?

RebelEM

Time to antibiotic therapy (from triage, not from onset of infection) has become a quality metric to improve the time to administration of these medications. Prehospital Administration of Broad-Spectrum Antibiotics for Sepsis Patients: A Systematic Review and Meta-Analysis. Paper: Varney J et al. to 0.97; p = 0.02 to 2.07; p = 0.91

Sepsis 132
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Amikacin for Ventilator-Associated Pneumonia (AMIKINHAL trial)

PulmCCM

In 2008, the U.S. Hospital administrators put VAP on the kill list. ICUs, and a popular research focus for academics, generating a steady stream of papers. Then, in 2009, the condition disappeared completely. Just kidding! Its incidence was closely tracked, and nonprofit organizations provided bundles for how to eradicate it.

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Diagnostics and Therapeutics: Vascular Access in the Emergency Department

Taming the SRU

Establishing reliable vascular access is absolutely critical for ED patients requiring resuscitation, airway management, or medication administration. IOs can be used both for resuscitation, medication administration, and for laboratory testing, but there are a few important considerations. 2008 Jan;26(1):31–8. Li Y, editor.

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Hyponatremia

Northwestern EM Blog

Of note, you do NOT need a central line for hypertonic saline administration. Though if your administration says differently, do not waste time putting in a triple lumen catheter if hypertonic is truly indicated in your hyponatremia patient. 2008 Nov;3(6):1852-60. Epub 2008 Aug 6. Crit Care Nurse. 2021 Feb 1;41(1):25-30.

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A Relatively Narrow Complex Tachycardia at a Rate of 180.

Dr. Smith's ECG Blog

The supposition that beta blockade in the presence of cocaine intoxication would lead to unopposed alpha constriction is not based in accurate pharmacology, and the study that showed this effect with human intracoronary administration was done, as mentioned in the article, with propranolol, a nonselective beta blocker. Cigarroa, R.G.