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ToxCard: Bupropion

EMDocs

3 Bupropion blocks the reuptake of dopamine and norepinephrine, as well as antagonizes acetylcholine at nicotinic receptors. Bupropion lowers the seizure threshold and even at therapeutic doses patients can have seizures. 6 In one study, almost all patients who went on to develop seizures had tachycardia prior to the seizure.

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Fluoroquinolone Use In Children

Pediatric EM Morsels

Noel 2007) In a very robust, recent multicenter, randomized, double-blind controlled study Moxifloxacin was compared to a comparator drug (IV ertapenem followed by PO Augmentin) for complex intraabdominal infections. None of the patients were documented to have joint disease at follow up. 451 pediatric patients were included. 26(10):879-91.

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ACMT Toxicology Visual Pearls: Mushroom Mishap

ALiEM

What well-known adverse reaction results from ingestion of the pictured mushroom? Acute hepatitis Disulfiram-like reaction with ethanol consumption Pneumonitis from inhalation of spores Seizures from glutamate agonist activity [Image from Canstockphoto] Reveal the Answer 2. 2007 Mar;5(1):64-74. Antimicrob Agents Chemother.

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Diagnostics: The Shunt Series

Taming the SRU

He appears well and is triaged to an ESI 4. Case 2 19 year old seizure A 19-year-old male is brought into your emergency department via EMS for witnessed seizure-like activity. The seizure abated with rectal diazepam given by the squad. You notice a med-alert bracelet with the patient’s name and the word “SEIZURES.”

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Brain Trauma Guidelines for Emergency Medicine

ACEP Now

This document is an update of guidelines first published in 2000, and then updated in 2007. Confounders to the GCS such as seizure and post-ictal phase, ingestions and drug overdose, as well as medications administered in the prehospital setting that impact GCS score should be documented.

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Blood Pressure Management in Neurologic Emergencies: What Does the Evidence Say?

EMDocs

However, other sources suggest that the optimal blood pressure target is not well established and may vary depending on the individual patient’s characteristics and the type of hemorrhagic transformation [7]. 2007 Jul 18;2007(3):CD000277. This includes intraparenchymal hemorrhage and subarachnoid hemorrhage (SAH). doi: 10.1212/wnl.50.4.876.

Stroke 101
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Beyond Ketamine: When to use Facilitated Intubation in the ED

EMDocs

They increase the risks of hypoxia and acidosis during the apneic period as well as hypotension and hypoperfusion caused by the abrupt transition from negative-pressure to positive-pressure ventilation (10). Contraindicated seizures or porphyria. 2007): 748. Minimal histamine release. Cons: Short duration of action.