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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

2007 Jul-Aug;28(4):418-26. PMID: 32653333 What They Did Multi-center, double-blind, randomized, phase 3 clinical trial with a parallel-group, active-controlled, non-inferiority design. Patients were randomized in a 1:1 ratio. The effectiveness of IV cetirizine was determined to be statistically non-inferior. Allergy Asthma Proc. 2, 2001, pp.