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Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?

RebelEM

The risk of a biphasic reaction is what keeps patients in the ED while being observed for a set period of time. The overall incidence of biphasic reactions is unknown with rates quoted from < 0.5% up to 23% ( Lieberman 2005 , Rohacek 2014 , Tole 2007 , Grunau 2014 ). Biphasic Anaphylactic Reactions. Read More: 1.

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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Noninferiority trials, covered here on REBEL EM , are helpful when the experimental treatment offers a distinct advantage over the standard treatment. 2007 Jul-Aug;28(4):418-26.