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The US FDA's cancer drug approval process is broken and needs audit

Sensible Medicine

Selenexor is a toxic poison that does not increase survival. In the latest project from our team , led by medical student Josh Elbaz, we examine how many FDA approvals from 2006 to 2023 improve survival. Unfortunately, you can approve bad drugs. Note the time from safety alert to withdrawal, and when the data was generated.

Poisoning 128
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ACMT Toxicology Visual Pearl – Apricot Kernels: Eat or pass?

ALiEM

Although poisoning by ingestion of cyanogenic foods is much more common in tropical countries, there have been reported cases in the US [1, 3]. What are the symptoms of cyanide poisoning? How to you treat cyanide poisoning? [1, Hydroxocobalamin is the preferred antidote for cyanide poisoning. 2006 ;118(5):2146-58.

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Annals of B Pod: Social EM Corner- Suicide Related Behaviors

Taming the SRU

In conjunction with the Drug and Poison Information Center (DPIC), intravenous methylene blue was initiated for suspected methemoglobinemia with moderate improvement of her symptoms over the next hour, including return of baseline mental status and resolution of hypoxia. Emergency Department Visits Related to Suicidal Ideation, 2006-2013.

EMS 96
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Toxicology Answer: An Illustrated Case of Ethylene Glycol, Direct and Indirect

ACEP Now

The patient’s urine was obtained and compared with the urine of his emergency physician using a Wood’s lamp, and the patient’s was found to be brightly fluorescent, supporting the presumptive diagnosis of EG poisoning. After resolution of EG poisoning, he was transferred to psychiatry and ultimately discharged home without complication.

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PEMPix 2023 Online Case 4: You Can’t Get Fooled Again

PEMBlog

Cannabinoid poisoning D. 2006 Jul 24 [Updated 2017 May 25]. Based on his x-ray and abnormal labs, a CT of his abdomen and pelvis was also obtained with one relevant image shown here: A. Hepatic cancer B. Hepatic hemangioma C. Entamoeba histolytica infection E. Tyrosinemia Click here to reveal the correct answer E. Rashad MM, Nassar C.

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Episode 20 - Emergency Department Management of North American Snake Envenomations

EB Medicine

Both are at the University of Florida Jacksonville, and they reviewed a total of 120 articles from 2006-2017, in addition to reviews from both Cochrane and Dare. As some background, from 2006-2015 there were almost 66,000 reported snake exposures and 31 deaths from snake envenomation in the US. Jeff: What a team! 1-800-222-1222.

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Glasgow Coma Scale in Children

Pediatric EM Morsels

We have mentioned the Glasgow Coma Scale in multiple delicious morsels: Minor closed head injuries in <3 month olds and in the rebaked morsel , Blunt cerebrovascular injury , Cerebral edema in DKA , Pediatric Trauma Pitfalls , and Carbon monoxide poisoning. 2006 May;34(5):379-87. When is it useful and what does it tell us?