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The AcT Trial: Tenecteplase vs Alteplase for Acute Ischemic Stroke

RebelEM

Background : Alteplase, a class of medication that converts plasminogen to plasmin leading to fibrin degradation and subsequent clot lysis, has been the standard of care for acute ischemic stroke (AIS) patients that meet eligibility criteria. mg/kg non-inferior to alteplase in the treatment of acute ischemic stroke? vs Alteplase 34.8%

Stroke 135
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Blood Pressure Management in Neurologic Emergencies: What Does the Evidence Say?

EMDocs

This article will discuss blood pressure goals and preferred pharmacotherapy for non-traumatic ischemic and hemorrhagic strokes. Ischemic Strokes: Ischemic stroke is characterized by a blockage of a blood vessel in the brain. The BP targets for patients with ischemic strokes depend on the available therapeutic options.

Stroke 99
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Glasgow Coma Scale in Children

Pediatric EM Morsels

2005): 814–819. Epub 2016 Aug 1. PMID: 27197686. Holmes, James F et al. Performance of the Pediatric Glasgow Coma Scale in Children with Blunt Head Trauma.” Academic emergency medicine 12.9 Chung CY, Chen CL, Cheng PT, See LC, Tang SF, Wong AM. Critical score of Glasgow Coma Scale for pediatric traumatic brain injury. Pediatr Neurol.

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The PROPHY-VAP Trial: Ceftriaxone to Prevent VAP in Patients with Acute Brain Injury

RebelEM

3, 6 Among patients with stroke or traumatic brain injury (TBI), the risk may be as high as 28%-76% and 23%-60%, respectively. Patient data anonymized when presented to adjudication committee to avoid detection bias Well-balanced patient characteristics between groups. Post-stroke infection: a systematic review and meta-analysis.

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The Latest in Critical Care, 1/22/24 (Issue #26)

PulmCCM

This was in large part due to the recommendations from a task force of the International Liaison Committee on Resuscitation (ILCOR) , and their enshrinement in the American Heart Association’s 2005, 2010 and 2015 post-cardiac arrest management guidelines. that would create a rationale strong enough to justify the downsides of cooling?

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Contrast Media Shortage of 2022 – Lessons Learned

EMDocs

3 A study of CT use trends in the ED has shown increasing use of CTs by almost 60% from 2005 to 2013. 3 A study of CT use trends in the ED has shown increasing use of CTs by almost 60% from 2005 to 2013. Some institutions developed a tier-based system for outpatient imaging as well which was updated in real-time.

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Targeted temperature management for post-cardiac arrest is officially over (for now)

PulmCCM

This was in large part due to the recommendations from a task force of the International Liaison Committee on Resuscitation (ILCOR) , and their enshrinement in the American Heart Association’s 2005, 2010 and 2015 post-cardiac arrest management guidelines. that would create a rationale strong enough to justify the downsides of cooling?