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Fluoroquinolone Use In Children

Pediatric EM Morsels

Gatifloxacin use was evaluated in 867 children, which resulted in 12 (1.4%) of children having transient arthritis which resolved within 2 weeks (Pichichero 2005) Ciprofloxacin was compared to Cephalospoin for the treatment of complicated UTI’s in children. BMC Infectious Disease. Arthropathy was seen in 13.7% Clin Infect Dis.

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The resurgence of vaccine preventable infections: Measles and Pertussis

Don't Forget the Bubbles

Whooping Cough: A Cyclical but Preventable Disease Whooping cough, caused by the bacterium Bordetella pertussis , is another infectious disease experiencing a resurgence despite the availability of vaccines. Clin Microbiol Rev 2005; 18 :32682 Mooi FR, van der Maas NAT, de Melker HE. Epidemiol Infect.

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Discitis

Don't Forget the Bubbles

Infectious spondylodiscitis. Clinical Infectious Diseases. 2005 May;72. Yield of Image-Guided Needle Biopsy for Infectious Discitis: A Systematic Review and Meta-Analysis. The Journal of Bone and Joint Surgery British volume. 2001 Jan;83-B. Cottle L, Riordan T. Journal of Infection. 2008 Jun;56. Cushing AH.

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Diagnostics: Inflammatory Markers

Taming the SRU

Spinal Infection: According to the Infectious Disease Society of America’s (IDSA) 2015 guidelines for native vertebral osteomyelitis, CRP and ESR in the setting of protracted back pain have sensitivities ranging from 94 to 100% for ruling out infection and malignancy in these patients. 2005 Nov;6(11):1045-56. doi: 10.1631/jzus.2005.B1045.

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Two Big Changes in Community Acquired Pneumonia Treatment

ACEP Now

Categories of pneumonia have included CAP, hospital-acquired (HAP), ventilator-associated (VAP), and, beginning in 2005, health care-acquired (HCAP). As a result, the 2019 guidelines from the Infectious Disease Society of America (IDSA) significantly rein in those patients who should receive empiric coverage for MRSA or P.

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The PROPHY-VAP Trial: Ceftriaxone to Prevent VAP in Patients with Acute Brain Injury

RebelEM

Am J Respir Crit Care Med 2005 , 171 (4), 388-416. SECONDARY OUTCOMES At day 28 , ceftriaxone group had (vs placebo): Lower VAP risk (20% vs 36%); hazard ratio 0.62 coli Need for broad-spectrum antibiotics after randomization was not different between groups. DOI: 10.1056/NEJMoa1812379 From NLM. (9) DOI: 10.1164/rccm.200405-644ST

CDC 122
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Symptomatic Bradycardia: Considering the Differential Diagnosis

Northwestern EM Blog

Myocardial Infarction Medication Sinus node dysfunction Infectious Disease Hypothermia Metabolic Abnormalities (hypothyroidism, hyperkalemia, ect.) CARDIAC OUTPUT = STROKE VOLUME X HEART RATE Treatment Algorithm for Symptomatic Bradycardia [2-4]: What are common causes of symptomatic bradycardia [2]? link] Farkas, J. 2021, October 1).