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Bullous Skin Lesions, Meet Emergency Medicine

Taming the SRU

Mortality rates related to bullous skin lesions are typically related to disruption of the skin barrier and include subsequent dehydration, electrolyte imbalances, hypothermia, increased metabolic needs, and secondary infection leading to bacteremia and/or sepsis. Nature 2004; 428:486. DIC is an uncommon but potential complication.

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Adjunctive Methylene Blue in Septic Shock?

RebelEM

Background: Sepsis can induce numerous physiologic derangements. The Influence of Methylene Blue infusion on Cytokine Levels During Severe Sepsis. Crit Care 2004. At the most severe end, this includes endothelial dysfunction leading to increased vascular permeability, abnormal nitric oxide metabolism, and vasodilation (i.e.

Shock 145
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Diagnostics: Inflammatory Markers

Taming the SRU

However, PCT can be elevated in severe trauma, such as burns or surgery [5,25]. Bacterial Meningitis: IDSA guidelines for 2004 report that a normal CRP value has a high negative predictive value for bacterial meningitis, but sensitivities and specificities vary between studies [35]. days (secondary endpoint) [51]. Procalcitonin.

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Vasopressor Nonresponse

Northwestern EM Blog

Acidosis Acidosis in shock states can present from multiple different sources, including sepsis, hypoxemia, ingestions, hyperlactatemia from hypoperfusion, amongst others. Those at higher risk of hypocalcemia (vitamin D deficiency, ESRD, hyperparathyroidism, burns, multiple blood transfusions, etc.) 2004; 139(11):1199-1203.