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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review. 2004 Feb;113(2):347-52. Resources: Banerji A, Long AA, Camargo CA Jr.