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Clinical Conundrums: Should You Give the First Dose of Antibiotics IV Before Discharging Home on Oral Antibiotics?

RebelEM

Except for patients with poor gut absorption or those with critical infectious processes such as septic shock or necrotizing fasciitis, this belief appears to be unfounded. Oral administration of antibiotics: a rational alternative to the parenteral route. Lancet 2004; 364: 1141-8. 1997; 24(3):457-67.

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The Pediatric Surgical Abdomen

Pediatric Emergency Playbook

2004; 199(4):628-635. Plasma levels of lidocaine following nebulized aerosol administration. 2004 Aug;44(2):131-7. Intestinal Malrotation in Children: A Problem-Solving Approach to the Upper Gastrointestinal Series. Radiographics. 2006; 26:1485-1500. Kapfer SA, Rappold JF. J Am Coll Surg. Lee HC et al. J Emerg Med. Pediatrics.

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How to prevent central line infections

PulmCCM

per 1,000 catheter-days in a 2004 analysis across Michigan (or about 1 infection for every 40 people with a CVC for 10 days). These measures have dramatically increased hospital administrators’ attention to CLABSI rates, and have likely had an effect of reducing actual rates of CRBSI. CLABSI rates were about 2.5

CDC 52
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Neonatal Jaundice

Pediatric Emergency Playbook

Also, newborns have a double-whammy administrative load. He will be dehydrated – possibly in shock. 2004; 114(1). Newborns are terrible at answering emails. There is a lot of unread unconjugated bilirubin is floating around. The liver and spleen are just not able to keep up. He will be irritable. Pediatrics. Bhutani V et al.

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Adjunctive Methylene Blue in Septic Shock?

RebelEM

septic shock). Judicious fluid resuscitation is indicated in patients with signs of hypo perfusion but is often inadequate necessitating the administration of vasoactive medications. Limited, small studies on its use in septic shock do not make a clear argument for use. Paper: Ibarra-Estrada, M et al. Crit Care 2023.

Shock 145
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An Herbal Hope: Is XBJ A Game-Changer in Sepsis Management?

RebelEM

4 XBJ received approval from the China Food and Drug Administration in 2004, 2 although the FDA of the United States has not approved it. in both groups Mean APACHE II score was 12 in both groups Almost half of the patients had septic shock at enrollment Mean time from sepsis identification to randomization was 1.4 J Clin Med.

Sepsis 98
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REBEL Core Cast 122.0 – Neutropenic Fever

RebelEM

Early administration of antibiotics is the only factor known to reduce this mortality. Early administration of antibiotics is the only factor known to reduce this mortality. Cohort Study of the Impact of Time to Antibiotic Administration on Mortality in Patients with Febrile Neutropenia. Radiologypics, P. 2014, November 10).