article thumbnail

Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Studies funded by pharmaceutical companies are four times more likely to have favorable results than studies from other sources (Lexchin 2003). Allergy Asthma Proc. PMID: 17883909.