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Rebaked: Inborn Errors of Metabolism presenting in the ED

Pediatric EM Morsels

2000; 105:e 10. There may be an occasion when a patient is lower risk that the sub-specialist is comfortable treating as an outpatient, but realize they are not NO risk. References: Applegarth DA , Toone JR , Lowry RB. Incidence of inborn errors of metabolism in British Columbia, 1969–1996. Pediatrics. Samantha A. Schrier Vergano.

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Glasgow Coma Scale in Children

Pediatric EM Morsels

Pediatric adjusted reverse shock index multiplied by Glasgow Coma Scale as a prospective predictor for mortality in pediatric trauma. Fun fact for animal lovers!- cats and dogs have their own GCS scores [Lapsley 2019, Ash 2018] Moral of the Morsel Modified can make it Merrier! 2008 Apr;39(4):1347-8. doi: 10.1161/STROKEAHA.107.498345.

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REBEL Cast Ep116: The CLOVERS Trial – Restrictive vs Liberal Fluids in Sepsis-Induced Hypotension

RebelEM

Background: IV fluids are part of the standard resuscitation bundle in septic shock, however it is unclear if they provide a significant benefit. The goal of the trial was to see if early vasopressors improved shock control by 6 hours. This resulted in better shock control by 6hrs (76.1% Liberal: 14.9%

Sepsis 105
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Clinical Conundrum: Should We Always Treat Fever in Patients with Sepsis?

RebelEM

A large observational study of > 2000 patients found an association with fever at presentation and ICU survival for patients with severe sepsis or septic shock ( Sunden-Culberg 2017 ). Importantly, all of the patients in this study had septic shock requiring vasopressors and mechanical ventilation.

Sepsis 55
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Electrical injuries

Don't Forget the Bubbles

Was the patient thrown from the source (suggestive of DC shock and may result in further blunt force trauma)? Children, especially toddlers, may insert objects into outlets, leading to shocks or burns. Electrical devices used near water sources can cause severe shocks. Was the voltage high or low (as below)?

Burns 80
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ACMT Toxicology Visual Pearl: Who Doesn’t Like a Nice Rosé?

ALiEM

Critical illness requiring intubation and propofol sedation Cyanide toxicity requiring sodium thiosulfate Iron toxicity treated with deferoxamine Refractory vasoplegic shock treated with methylene blue Septic shock treated with vancomycin and cefepime Reveal the Answer 3. 2000 Jun;59(6):1233-50. PMID 10575418 Kaakkola S.

Shock 64
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A Simple Study May Herald a Big Change in Evidence-Based Medicine

Sensible Medicine

In multiple centers, slightly more than 2000 patients were randomized to either early or later starting of the anticoagulant drugs. We are shocked at the response this newsletter has achieved. In other words—a composite of bad things that can occur from not treating (more clots) or treating (bleeding). in the later treatment arm.

Stroke 91