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52 in 52 – #37: POLAR trial – Hypothermia for Severe TBI

EMDocs

This week we cover the POLAR RCT on hypothermia for neuroprotection in those with severe TBI. Take Aways: The data do not suggest that targeted hypothermia improves neurological function, reduces death, or reduces hospital length of stay as compared to normothermia. Welcome back to the “52 in 52” series. Bradycardia: 18.8%

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A Simple Study May Herald a Big Change in Evidence-Based Medicine

Sensible Medicine

The conclusion therefore read that therapeutic hypothermia “did not confer a significant benefit in survival with a good functional outcome at 1 year.” In multiple centers, slightly more than 2000 patients were randomized to either early or later starting of the anticoagulant drugs. A primary outcome occurred in 2.9%

Stroke 98
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emDOCs Podcast – Episode 101: Acute Chest Syndrome Part 2

EMDocs

Hypothermia, hypotension, and vasoconstriction may affect pulse oximetry reading, which is based on light absorption from fingertip blood flow. National Acute Chest Syndrome Study Group [published correction appears in N Engl J Med 2000 Sep 14;343(11):824]. Pulse oximetry is also based on HbA, not HbS. N Engl J Med.

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Brain Trauma Guidelines for Emergency Medicine

ACEP Now

This document is an update of guidelines first published in 2000, and then updated in 2007. In April 2023, the third edition of the Brain Trauma Foundation’s evidence-based guidelines for the prehospital management of traumatic brain injury (TBI) was published in Prehospital Emergency Care.

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Seeing Peter Safar, and his work

Advanced Emergency Nursing from AENJ

Research into post-arrest after-care, therapeutic hypothermia, reanimatology. Helped establish the Freedom House ambulance with paramedic level care. Expanding focus of resuscitation to include the brain: CPCR; CardioPulmonary Cerebral Resuscitation. Support of prevention activities to lessen the need for resuscitation. H., & Tang, W.